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. 2019 Jun 11;9:8472. doi: 10.1038/s41598-019-44800-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Synteny around H3F3A and H3F3B genes. (A,B) Synteny conservation analysis around human H3F3A (A) and H3F3B (B) genes performed using selected actinopterygian genomes. Human H3F3A and H3F3B and actinopterygian H3.3 are placed at the center of each plot (green block). A black outline represents an ortholog of a gene in the same color, while a white outline represents a paralog of a gene in the same color. A blue star indicates an actinopterygian organisms in which syntenic genes around the H3.3 gene are also conserved around the human H3.3 gene.