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. 2019 Jun 5;10:686. doi: 10.3389/fphys.2019.00686

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Copyright © 2019 Li, Wu, Wei, Cai, Yan, Song, Wang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miR-186-5p levels in serum and myocardial tissues of AMI rats. (A) Relative levels of miR-186-5p in serum of AMI rats (n = 5 per group). Cq values of miR-186-5p were converted to relative levels normalized to spiked-in exogenous MIR2911 using the comparative Cq method (2^∧−ΔCq). Cq values of the exogenous MIR2911 in serum samples showed no significant difference among five groups. (B) Relative levels of miR-186-5p in ischemic myocardium of AMI rats (n = 5/group). Cq values of miR-186-5p were converted to relative levels normalized to endogenous U6 using the comparative Cq method (2^∧−ΔCq). Cq values of endogenous U6 in myocardial tissues showed no significant difference among five groups. Compared with the sham-operated group, ^*p < 0.05; ^∗∗p < 0.01.