TABLE 2.
The dynamic changes of biochemical indexes in ACS patients before and after PCI.
Variables | Before PCI (n = 92) | 1 day after PCI (n = 53) | 2 days after PCI (n = 20) | 3 days after PCI (n = 22) | 4 to 7 days after PCI (n = 28) | pa | pb | pc | pd |
TC, mmol/l, mean (SD) | 4.49(0.97) | 4.12(0.78) | 3.82(0.48) | 3.69(0.99) | 3.79(0.74) | <0.001 | 0.180 | 0.180 | 0.423 |
TG, mmol/l, median (IQR) | 1.54(1.01–2.08) | 1.45(1.02–1.86) | 1.20(1.10–2.47) | 1.05(0.86–1.95) | 1.88(1.27–4.89) | 0.078 | 0.655 | 0.655 | 0.317 |
HDL-C, mmol/l, mean (IQR) | 0.96(0.89–1.22) | 0.97(0.85–1.16) | 0.98(0.90–1.26) | 0.89(0.73–1.09) | 0.83(0.74–0.95) | 0.593 | 0.910 | 0.500 | 0.500 |
LDL-C, mmol/l, mean (SD) | 2.54(0.69) | 2.49(0.70) | 2.53(0.80) | 2.18(0.92) | 2.28(0.98) | 0.109 | 0.689 | 0.500 | 0.500 |
GLU, mmol/L, median (IQR) | 7.95(6.13–11.15) | 6.60(5.70–8.73) | 6.85(5.55–10.25) | 6.90(5.75–10.30) | 6.70(6.00–8.70) | 0.002 | 0.575 | 0.009 | 0.044 |
NLR, median (IQR) | 3.40(2.06–6.41) | 4.60(2.93–6.27) | 4.25(2.27–5.09) | 4.44(2.32–5.83) | 4.22(2.87–5.83) | 0.975 | 0.314 | 0.112 | 0.983 |
PLR, median (IQR) | 114.7(79.7–178.7) | 127.8(99.57–175.4) | 156.6(98.49–192.4) | 127.5(82.53–172.8) | 137.4(108.7–177.7) | 0.213 | 0.721 | 0.286 | 0.244 |
SII, median (IQR) | 689.8(423.4–1203.7) | 880.2(671.6–1239.7) | 688.8(440.1–1414.2) | 941.3(526.5–1203.0) | 876.7(707.7–1338.9) | 0.765 | 0.722 | 0.255 | 0.841 |
ALB, g/L, median (IQR) | 41.60(37.65–43.90) | 38.50(36.75–41.20) | 37.50(35.90–40.90) | 38.60(33.48–40.30) | 39.15(35.52–40.80) | 0.001 | 0.161 | 0.084 | 0.003 |
DD, mg/L, median (IQR) | 0.32(0.19–0.50) | 0.38(0.23–1.18) | 0.48(0.27–0.93) | 0.26(0.18–1.04) | 0.45(0.22–0.97) | 0.170 | 0.068 | 0.917 | 0.260 |
NT-pro-BNP, pmol/L, median (IQR) | 31.30(6.38–159.73) | 87.20 (47.80–219.00) | 169.40 (116.20–302.50) | 130.75(39.13–498.03) | 77.80(34.70–252.48) | 0.011 | 0.114 | 0.239 | 0.012 |
cTnI, ng/ml, median (IQR) | 0.25(0.05–5.89) | 23.98(11.90–50.00) | 16.86(0.57–42.88) | 5.46(2.34–23.52) | 5.47(1.01–9.83) | <0.001 | 0.161 | 0.314 | 0.196 |
CK, IU/L, median (IQR) | 113.0(75.50–322.00) | 975.00(147.00–2373.00) | 262.00(84.25–1168.25) | 210.00(50.00–402.00) | 120.00(85.00–237.00) | 0.001 | 0.594 | 0.917 | 0.841 |
CK-MB, IU/L, median (IQR) | 16.00(6.00–38.00) | 100.00 (21.00–211.00) | 32.00(7.25–65.50) | 15.00(7.50–25.00) | 11.00(8.00–15.75) | 0.001 | 0.814 | 0.349 | 0.513 |
Grace scores, mean (SD) | 144.0(33.0) | 104.6(23.8) | 110.4(30.0) | 108.6(27.1) | 99.5(25.8) | <0.001 | <0.001 | <0.001 | <0.001 |
PCI, percutaneous coronary intervention; SD, standard deviation; IQR, interquartile range; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, high-density lipoprotein cholesterol; GLU, glucose levels upon admission; NLR, neutrophil-lymphocyte ratio; PLR, platelet-lymphocyte ratio; SII, immune inflammation index; ALB, serum albumin; DD, plasma D-dimer; NT-pro BNP, N-Terminal-pro-B-Type Natriuretic Peptide; cTnI, cardiac troponin I; CK, ckinase; CK-MB, ckinase-MB; aBefore PCI vs. 1 day after PCI, bBefore PCI vs. 2 days after PCI, cBefore PCI vs. 3 days after PCI, dBefore PCI vs. 4 to 7 days after PCI.