Table 3.
Associations of the clinical features with complications in pediatric PM patients analyzed by chi-squared test
| Parameters | Subgroups | Complications | Chi-squared | P-value | |
|---|---|---|---|---|---|
| NO | YES | ||||
| Sex | Male | 21 | 23 | 0.061 | 0.805 |
| Female | 40 | 48 | |||
| Age | ≤28 months) | 34 | 60 | 13.247 | 0.000 |
| >28 months | 27 | 11 | |||
| Duration of disease | ≤4 days | 37 | 48 | 0.691 | 0.406 |
| >4 days | 24 | 23 | |||
| Consciousness state | Normal | 44 | 42 | 2.488 | 0.288 |
| Decline in consciousness | 10 | 16 | |||
| Coma | 7 | 13 | |||
| Convulsions on admission | NO | 46 | 36 | 8.511 | 0.004 |
| YES | 15 | 35 | |||
| Respiratory failure | NO | 56 | 67 | 0.339 | 0.560 |
| YES | 5 | 4 | |||
| MODS | NO | 59 | 68 | 0.081 | 0.776 |
| YES | 2 | 3 | |||
| Mechanical ventilation | NO | 56 | 61 | 1.129 | 0.288 |
| YES | 5 | 10 | |||
| Septic shock on admission | NO | 58 | 67 | 0.033 | 0.855 |
| YES | 3 | 4 | |||
| Adjuvant steroid therapy | NO | 16 | 18 | 0.013 | 0.909 |
| YES | 45 | 53 | |||
| Antibiotics treatment | Early | 15 | 12 | 1.192 | 0.275 |
| Late | 46 | 59 | |||
| WBCs in blood | High | 48 | 36 | 11.104 | 0.001 |
| Low | 13 | 35 | |||
| WBCs in CSF | High | 15 | 18 | 0.010 | 0.920 |
| Low | 40 | 50 | |||
| Glucose in CSF | High | 24 | 28 | 0.000 | 0.991 |
| Low | 37 | 43 | |||
| Protein in CSF | Low | 28 | 38 | 1.515 | 0.218 |
| High | 29 | 25 | |||
| Predisposing factors | NO | 22 | 12 | 6.301 | 0.012 |
| YES | 39 | 59 | |||
| Concomitant disease | NO | 38 | 46 | 0.030 | 0.863 |
| YES | 22 | 25 | |||
Note: Bold, indicates P<0.05.
Abbreviations: PM, pneumococcal meningitis; MODS, multiple organ dysfunction syndrome; CSF, cerebrospinal fluid; WBC, white blood cell.