Table 6.
Distribution of the frequency of adverse events that occurred in patients during the treatment
| Side effects | Group I | Group II | P value |
|---|---|---|---|
| N (%) | N (%) | ||
| Thrombocytopenia | 14 (40) | 16 (45.7) | A0.63 |
| Leukopenia | 17 (48.6) | 18 (51.4) | A0.81 |
| Anemia | 4 (11.4) | 2 (5.7) | B0.34 |
| Flu like symptoms | 12 (34.3) | 4 (11,.4) | A0.023* |
| Loss of appetite and weight loss | 18 (51.4) | 13 (37.1) | A0.23 |
| Hair loss | 7 (20) | 1 (2.9) | B0.027* |
| Hypothyreosis | 2 (5.7) | 1 (2.9) | B0.5 |
| Hyperthyreosis | 1 (2.9) | 1 (2.9) | B0.75 |
| Nausea, vomitus | 1 (2.9) | 1 (2.9) | B0.75 |
| Fatigue, malaise | 6 (17.1) | 4 (11.4) | B0.49 |
| Cutaneous allergic reaction to the drug | 1 (2.9) | 0 | B0.5 |
| Dry skin | 2 (5.7) | 0 | B0.25 |
| Vertigo | 1 (2.9) | 0 | B0.5 |
| Infection | 1 (2.9) | 0 | B0.5 |
| Anxiety | 10 (28.6) | 7 (20) | A0.4 |
| Depression | 1 (2.9) | 0 | B0.5 |
| Skin changes | 3 (8.6) | 1 (2.9) | B0.31 |
| Headache | 1 (2.9) | 1 (2.9) | B0.75 |
| Insomnia | 1 (2.9) | 2 (5.7) | B0.5 |
Group I (with Atorvastatin); group II (without Atorvastatin); ap (Chi-square test); bp (Fisher exact test);
*
p < 0.05.