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. 2019 Jun 6;11:5243–5254. doi: 10.2147/CMAR.S196355

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© 2019 Chen et al.

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ELF-1 promoted aggressive cell phenotypes involving CCR2 in NPC cells. (A and D) ELF-1-TW01 and ELF-1-TW04 NPC cells were grown to confluence and treated with RS 102895 (RS; 10 mM) for 48 hrs. Cell growth was determined using the MTT assay. (B, C, E, and F) The cells were seeded into the upper chamber of a Transwell in the absence or presence of Matrigel and migration and invasion were assessed at 24 hrs post incubation. The results are expressed as the mean±SD of triplicate wells in three independent experiments. **p<0.01; ***p<0.001.

Abbreviations: CCL2, C-C motif chemokine ligand 2; CCR2, C-C chemokine receptor 2; MTT, 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NPC, nasopharyngeal carcinoma; SD, standard deviation.