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. 2019 Apr 30;7(5):119. doi: 10.3390/microorganisms7050119

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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LMP1 amino acid sequences of EBV strains derived from Japanese NPC patients. (a) Varying amino acid sequences among LMP1 derived from Japanese EBV strains from NPC patients (Pt1, Pt2, and Pt3) and other representative EBV strains. Numbers correspond to amino acid positions within LMP1_B95-8. Amino acid changes are denoted by letter changes; a dash represents a deletion. Strains harboring amino acid changes are shown in bold and shaded in different colors. Unique amino acids found in China 1 or China 2 are shown in red. The position of the 33 bp repeats is denoted at the top. LMP1 sequences were retrieved from GenBank. Accession numbers are as follows: B95-8, V01555; CAO, AF304432; Akata, KC207813; SNU-719, AP015015; YCCEL1, AP015016; M81, KF373730; NPC1, EF419184; NPC15, AY601321; Pt1, LC467962; Pt2, LC467963; Pt3, LC467964. (b) Phylogenetic tree constructed from the LMP1 amino acid sequences of Japanese NPC-derived EBV strains and other representative EBV strains.