Table 2.
Distribution of virulence genes in K. pneumoniae isolates from community-acquired urinary tract infections (CA-UTI) and hospital-acquired urinary tract infections (HA-UTI).
Virulence Factor | Target Gene | Nr. of CA-UTI Isolates (%) | Nr. of HA-UTI Isolates (%) | Total (%) | |
---|---|---|---|---|---|
(n = 50) | (n = 31) | (n = 81) | |||
Fimbrial adhesins | Type 1 | fimH | 20 (40.0) | 31 (100.0) * | 51 (63.0) |
Type 3, variant 1 | mrkDV1 | 10 (20.0) | 30 (96.8) * | 40 (49.3) | |
Type 3, variant 2-4 | mrkDV2-4 | 31 (62.0) | 0 * | 31 (38.2) | |
Toxin | Haemolysin | khe | 23 (46.0) | 26 (83.9) * | 49 (60.5) |
Capsular type | K2 serotype | K2A | 3 (6.0) | 10 (32.2) * | 13 (16.0) |
Siderophore | Aerobactin | iucC | 10 (20.0) | 5 (16.1) | 15 (18.5) |
Protectins or invasins | Mucoviscosity phenotype | magA | 0 | 0 | 0 |
Regulator of mucoid phenotype | rmpA | 0 | 0 | 0 |
Legend: CA-UTI, community-acquired urinary tract infection; HA-UTI, hospital-acquired urinary tract infection; Nr., number; * p-values less than 0.05 were considered statistically significant.