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. 2019 May 20;3:149. Originally published 2018 Nov 19. [Version 3] doi: 10.12688/wellcomeopenres.14863.3

Table 3. Final multivariable model of factors independently associated with estimated glomerular filtration rate <60 ml/min per 1.73m 2.

Variable Adjusted OR (95% CI) 1
Sex P=0.56
Male Reference
Female 1.19 (0.64–2.24)
Age Group P<0.001
<35 Reference
35–44 0.53 (0.05–5.14)
45–54 3.49 (0.86–14.09)
55–64 5.73 (1.47–22.25)
65–74 12.24 (3.27–45.82)
75 + 29.68 (7.99–110.19)
Blood Pressure * 2 P=0.05
Normal Reference
Pre-Hypertension 1.92 (0.81–4.57)
Hypertension 2.86 (1.15–7.08)
Anaemia 3 P=0.02
Negative Reference
Positive 2.14 (1.12–4.09)

*Variables from a previous round (R22) of the GPC where total number of participants may vary: Blood Pressure (n=3,039).

1Multivariable model adjusted for age, sex and all independent predictors of eGFR <60mls/min per 1.73 m 2. OR, odds ratio; 95% CI, 95% confidence interval. 2Blood pressure classification derived from the National Institute of Health guidelines: Pre-Hypertension was defined as having a systolic blood pressure greater than 120 mmHg but less than 140 mmHg, and a diastolic blood pressure greater than 80 mmHg but less than 90 mmHg. Hypertension was defined as having a systolic blood pressure (BP) greater than or equal to 90mmHg, diastolic BP greater than or equal to 140mmHg. 3Anaemia was defined as having haemoglobin levels less than 130 g/l in men, 120 g/L in non-pregnant women, and 110 g/l in pregnant women. Only 2,064 individuals had anaemia results from the R24 of the GPC