Table 3. Final multivariable model of factors independently associated with estimated glomerular filtration rate <60 ml/min per 1.73m 2.
Variable | Adjusted OR (95% CI) 1 |
---|---|
Sex | P=0.56 |
Male | Reference |
Female | 1.19 (0.64–2.24) |
Age Group | P<0.001 |
<35 | Reference |
35–44 | 0.53 (0.05–5.14) |
45–54 | 3.49 (0.86–14.09) |
55–64 | 5.73 (1.47–22.25) |
65–74 | 12.24 (3.27–45.82) |
75 + | 29.68 (7.99–110.19) |
Blood Pressure * 2 | P=0.05 |
Normal | Reference |
Pre-Hypertension | 1.92 (0.81–4.57) |
Hypertension | 2.86 (1.15–7.08) |
Anaemia 3 | P=0.02 |
Negative | Reference |
Positive | 2.14 (1.12–4.09) |
*Variables from a previous round (R22) of the GPC where total number of participants may vary: Blood Pressure (n=3,039).
1Multivariable model adjusted for age, sex and all independent predictors of eGFR <60mls/min per 1.73 m 2. OR, odds ratio; 95% CI, 95% confidence interval. 2Blood pressure classification derived from the National Institute of Health guidelines: Pre-Hypertension was defined as having a systolic blood pressure greater than 120 mmHg but less than 140 mmHg, and a diastolic blood pressure greater than 80 mmHg but less than 90 mmHg. Hypertension was defined as having a systolic blood pressure (BP) greater than or equal to 90mmHg, diastolic BP greater than or equal to 140mmHg. 3Anaemia was defined as having haemoglobin levels less than 130 g/l in men, 120 g/L in non-pregnant women, and 110 g/l in pregnant women. Only 2,064 individuals had anaemia results from the R24 of the GPC