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editorial
. 2019 May;11(Suppl 9):S1329–S1332. doi: 10.21037/jtd.2019.04.22

Table 1. Clinical trials of mesenchymal stromal cells in ARDS.

Clinicaltrials.gov Country Cell type Placebo Dose Delivery Follow-up Patients
Published clinical trials
   NCT01902082 China AD-MSC Saline 106/kg IV 7 days 12 (6/6)
   NCT01775774 USA BM-MSC No 1, 5, 10×106/kg IV 12 months 9 (3/3/3)
   NCT02097641 USA BM-MSC Plasmalyte 107/kg IV 12 months 60 (40/20)
Ongoing clinical trials
   NCT02444455 China UC-MSC No 5×105/kg/day (3 days) IV 14 days 20
   NCT02112500 Korea BM-MSC No Not reported IV 28 days 10
   NCT02215811 Sweden BM-MSC No Not reported Not reported 12 months 10
   NCT02095444 China MB-MSC No 107/kg/week (2 weeks) IV 14 days 20
   NCT02611609 UK Multistem® Saline Not reported Not reported 12 months 36 (12/12/12)
   NCT03042143 UK UC-CD362 MSC Plasmalyte 1, 2, 4×108 cells IV 14 days 75
   NCT02804945 USA BM-MSC Plasmalyte 3×106 cell/kg IV 60 days 50
   NCT03608592 China UC-MSC Saline 60×106 cells IV 28 days 12
   NCT03818854 USA BM-MSC Cell reconstitution media 107 cells/kg IV 60 days 120

Mesenchymal stromal cell (MSC) clinical trials in ARDS patients. ARDS, acute respiratory distress syndrome; AD, adipose-derived; BM, bone marrow-derived; UC, umbilical cord-derived; MB, menstrual blood-derived; IV, intravenous.