Table 3.
Scores of sub-scales of QoL using random effect meta-analysis of data from reviewed studies
| Sub-scales of QoL | Number of studies | SEM estimates (CI%95) | SMD (CI%95) | Heterogeneity index I2 (%) | P value | |
|---|---|---|---|---|---|---|
| NF | Control | |||||
| Physical Function | 8 | 78.88 (70.19–87.58) | 89.76 (84.91–94.61) | - 43 (−61, −24) | 68.6 | 0.002 |
| Role Physical | 8 | 69.66 (55.09–84.23) | 80.93 (71.65–90.22) | − 0.28 (− 0.51, − 0.06) | 77.7 | 0.000 |
| Bodily pain | 9 | 71.74 (65.22–78.25) | 80.40 (75.41–85.40) | − 0.35 (− 0.52,−0.19) | 58.8 | 0.017 |
| Vitality | 6 | 50.06 (44.82–55.30) | 57.37 (53.48–61.26) | − 0.42 (− 0.63, −0.21); | 70.3 | 0.009 |
| Mental health | 8 | 63.83 (56.67–70.99) | 69.57 (65.20–73.94) | − 0.37 (− 0.59, −0.15) | 76.3 | 0.000 |
| Role emotional | 7 | 65.72 (51.91–79.53) | 77.07 (69.37–84.76) | −0.44 (− 0.57, −0.32 | 26.0 | 0.000 |
| Social functioning | 6 | 64.32 (54.14–74.51) | 75.32 (67.49–83.16) | −0.46 (− 0.57, −0.36) | 14.3 | 0.000 |
| General health | 8 | 57.31 (51.77–62.86) | 68.97 (63.88–74.06) | −0.65 (− 0.82, −0.47) | 65.5 | 0.005 |
| Family cohesion | 3 | 77.38 (73.19–81.57) | 78.06 (72.62–83.50) | −0.03 (− 0.39, 0.03) | 62.1 | 0.072 |