Table 2.
Absolute and relevant frequencies of outcomes of interest during follow-up in the total population and the two study groups of low- and high-Klotho
| Parameter | Total Population, n = 79 | Klotho≤745, n = 40 | Klotho> 745, n = 39 |
|---|---|---|---|
| Non fatal MI | 7 (8.9%) | 4 (10%) | 3 (7.7%) |
| Fatal MI | 7 (8.9%) | 4 (10%) | 3 (7.7%) |
| Non fatal Stroke | 5 (6.3%) | 0 (0%) | 5 (12.8%) |
| Fatal Stroke | 2 (2.5%) | 1 (2.5%) | 1 (2.6%) |
| Sudden death | 7 (10.1%) | 7 (17.5%) | 0 (0%) |
| Resuscitation after cardiac arrest | 1 (1.3%) | 0 (0%) | 1 (2.6%) |
| Coronary revascularization procedure | 6 (7.6%) | 2 (5%) | 4 (10.3%) |
| Hospitalization for acute decompensated heart failure | 2 (2.5%) | 1 (2.5%) | 1 (2.6%) |
| AF | 12 (15.2%) | 6 (15%) | 6 (15.4%) |
| Cardiovascular death | 16 (20.3%) | 12 (30%) | 4 (10.3%) |
| Non cardiovascular death | 19 (24.1%) | 9 (22.5%) | 10 (25.6%) |
| All-cause death | 35 (44.3%) | 21 (52.5%) | 14 (35.9%) |
| All-cause death or non-fatal MI or non-fatal stroke | 40 (50.6%) | 25 (62.5%) | 15 (38.5%) |
| Cardiovascular death or non-fatal MI or non-fatal stroke | 27 (34.2%) | 18 (45%) | 9 (23.1%) |
| Cardiovascular death, or non-fatal MI or non-fatal stroke or coronary revascularization or hospitalization for heart failure or AF | 37 (46.8%) | 23 (57.5%) | 14 (35.9%) |
| All cause death, or non-fatal MI or non-fatal stroke or coronary revascularization or hospitalization for heart failure or resuscitation after cardiac arrest, or AF | 48 (60.8%) | 30 (75%) | 18 (46.2%) |
Abbreviations: AF Atrial fibrillation, MI Myocardial infraction