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. 2019 Jun 12;14:55. doi: 10.1186/s13000-019-0834-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Distribution of CD163-positive M2 macrophages in Kazakh ESCC and CAN tissues. (a) and (b) showed the distribution of M2 macrophages in ESCC tumour stromal and islet, respectively. CD163 revealed diffuse staining of membranes and cytoplasm of M2 macrophages and showed the high density of M2 macrophages located in ESCC tissues (especially in tumour stroma). (c) and (d) showed the distribution of TAMs in CAN stroma and epithelia, respectively. A small number of CD163-positive M2 macrophages appear in CAN tissues