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Workflow of patient-derived CTCs for CTC analysis, drug-resistance detection, and personalized drug-delivery systems.
Notes: Patients’ blood samples are screened and potential CTCs captured and isolated. Potential CTCs can be enumerated, determined, and stained or cultivated for further analysis. CTC culture can be used for drug-resistance detection and personalized drug development, thereby increasing patient-survival rates.
Abbreviation: CTCs, circulating tumor cells.
