Table 3.
Value of kappa and precision of Beta-HPV types in agreement of anatomical sites from 717 men participating in the HPV Infection in Men Study.
| US | Brazil | Mexico | ||||
|---|---|---|---|---|---|---|
| Kappa1 (95%CI) |
Precision2
(%) |
Kappa (95%CI) |
Precision (%) |
Kappa (95%CI) |
Precision (%) |
|
| genital/anal canal | ||||||
| Beta-1 | ||||||
| HPV-19 | −0.011 (−0.023; −0.0002) | 97.48 | −0.007 (−0.021; 0.006) | 96.27 | 0.565 (0.123; 1) | 98.74 |
| HPV-93 | 0.277 (−0.162; 0.716) | 97.90 | NE | 99.59 | 0.434 (0.024; 0.844) | 97.90 |
| HPV-105 | 0.415 (0.088; 0.741) | 96.64 | 0.146 (−0.061; 0.353) | 92.12 | 0.396 (0.160; 0.632) | 93.28 |
| Beta-2 | ||||||
| HPV-22 | 0.163 (0.009; 0.318) | 81.09 | 0.169 (0.010; 0.328) | 85.48 | 0.469 (0.327; 0.610) | 84.45 |
| HPV-104 | NE | 97.90 | −0.007 (−0.017; 0.004) | 97.93 | 0.663 (0.225; 1) | 99.16 |
| Beta-3 | ||||||
| HPV-49 | 0.454 (0.159; 0.750) | 96.22 | 0.229 (0.006; 0.451) | 92.53 | 0.102 (0.087; 0.478) | 88.66 |
| HPV-76 | 0.244 (0.054; 0.434) | 88.24 | 0.525 (0.365; 0.685) | 90.04 | 0.236 (0.049; 0.422) | 87.82 |
| Beta-4 | ||||||
| HPV-92 | −0.008 (−0.017; −0.0002) | 98.32 | 0.663 (0.225; 1) | 99.17 | 0.665 (0.047; 1) | 99.58 |
| genital/oral cavity | ||||||
| Beta-1 | ||||||
| HPV-19 | −0.007 (−0.018; 0.004) | 97.90 | 0.216 (−0.139; 0.572) | 97.10 | 0.798 (0.411; 1) | 99.58 |
| HPV-36 | NE | 100 | −0.008 (−0.017; −0.0002) | 98.34 | 0.497 (−0.103; 1) | 99.16 |
| HPV-93 | 0.277 (−0.162; 0.716) | 97.90 | NE | 99.17 | 0.434 (0.024; 0.844) | 97.90 |
| Beta-2 | ||||||
| HPV-15 | 0.176 (−0.123; 0.475) | 96.22 | 0.231 (−0.049; 0.511) | 95.02 | 0.566 (0.127; 1) | 98.74 |
| oral cavity/anal canal | ||||||
| Beta-1 | ||||||
| HPV-14 | 0.665 (0.047; 1) | 99.58 | 0.189 (−0.141; 0.519) | 96.68 | NE | 100 |
| HPV-19 | −0.006 (−0.014; 0.002) | 98.74 | −0.004 (−0.010; 0.002) | 99.17 | 0.663 (0.225; 1) | 99.16 |
| HPV-47 | 0.565 (0.123; 1) | 98.74 | −0.006 (−0.016; 0.003) | 98.34 | 0.111 (−0.124; 0.347) | 94.54 |
| HPV-93 | −0.008 (−0.017; −0.0002) | 98.32 | 0.665 (0.047; 1) | 99.59 | 0.237 (−0.164; 0.638) | 97.48 |
| Beta-2 | ||||||
| HPV-75 | 0.497 (−0.103; 1) | 99.16 | −0.006 (−0.013; 0.002) | 98.75 | NE | 98.74 |
1
Kappa-kappa coefficient of concordance; 95%CI- 95% confidence intervals; NE-could not be evaluable. Strength of agreement is poor when of value of kappa is <0.000; slight when kappa among 0.000–0.200; fair when 0.210–0.400; moderate when 0.410–0.600; substantial when 0.610–0.800. Moderate or substantial agreements are in bold.
2
precision is percentage of agreement (number DNA negative or positive for the same type specific β-HPV in any two paired samples)/(total number of any two paired samples).