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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: J Mol Cell Cardiol. 2018 Nov 28;127:20–30. doi: 10.1016/j.yjmcc.2018.11.017

Figure 7: Efficiency and selectivity of AAV1.S2a gene delivery to the lung.

Figure 7:

A. Transgene copies were assessed by RT-PCR in RV and lung tissue samples to determine the efficiency and specificity of AAV1.S2a gene transfer to the lung. N=5-6 rats per group. ** P<0.01. B. Human and rat SERCA2a expression measured by RT-PCR in RV samples from CTRL, MCT, and MCT+S2a hearts. C. Representative immunofluorescence images and expression of SERCA2a (red) relative to α-actinin (green) in RV tissue sections from CTRL, MCT, and MCT+S2a hearts. D. Representative western blots of SERCA2a and GAPDH as a loading control, and quantification of relative SERCA2a protein expression in the RV of CTRL, MCT, and MCT+S2a hearts.