Table 1.
Participant Demographics by Site
Site |
Number of Participants (Females; Males) |
Range of Ages, Years (Median) |
Range of Visual Acuities (Snellen)a |
Range of Visual Acuities, Snellen Equivalent logMAR (Median) |
A | 10 (5; 5) | 10 to 70 (16.5) | 20/32 to 20/320 | 0.20 to 1.20 (0.45) |
B | 10 (5; 5) | 14 to 52 (30.5) | 20/20 to count fingersd | 0.0 to 1.85 (0.3) |
C | 9 (9; 0) | 7 to 39 (18) | 20/19 to 20/46 | −0.02 to 0.36 (0.1) |
The visual acuity values for the participants at site B were taken from the charts, not measured at the study visits. Visual acuities for the participants at the other two sites were measured at their first study visit.
USH II, Usher syndrome II; CRD, cone-rod dystrophy; LCA, Leber congenital amaurosis; RP, retinitis pigmentosa. Where known, the LCA gene mutation has been noted: RDH12, retinol dehydrogenase 12; CRB1, Crumbs 1.
Perimetry targets used in addition to the V4e target.
The conversion to logMAR for count fingers was based on Schulze-Bonsel et al.22