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(A) Representative T2-weighted MR coronal image of AAV transduced mouse brain. (B) Corresponding merged [18F]DASA-23 PET/MR images (5–30 min summed [18F]DASA-23 activity). White arrow indicates regions of radiotracer uptake, corresponding to the transduced region. (C) Ex vivo autoradiography of sagittal mouse brain sections excised 1 h after radiotracer administration. (D) An immunofluorescence staining for PKM2 protein in adjacent sagittal mouse brain section in C.
