Targets for consensus design. A representative structure of an extant sequence is shown for each target family (NTL9, 2HBB; SH3, 1LKK; SH2, 4U1P; DHFR, 5DFR; AK, 1ANK; PGK, 1PHP). Length of consensus sequence, biological function, and number of sequences used in final MSA are noted.