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. 2019 May 20;116(23):11299–11308. doi: 10.1073/pnas.1902490116

Fig. 4.

Fig. 4.

Changes in skeletal muscle glucose-handling gene expression and glycogen storage of Nurr1-mTg mice. (A) Expression of Glut4, Glut1, and G6pd mRNA in tibialis anterior muscle of WT and Nurr1-mTg mice after 10 wk on an HFD as detected by qRT-PCR. (B) Detection of glycogen in tibialis anterior muscle of WT and Nurr1-mTg mice by periodic acid–Schiff (PAS) staining after 10 wk on an HFD. (Scale bars, 50 μm.) (C) Quantification of glycogen content of quadriceps and gastrocnemius/plantaris (G/P) muscle of WT and Nurr1-mTg mice after 10 wk on an HFD. Data are represented as mean ± SEM. n = 6 for each genotype. *P < 0.05.