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. 2019 May 6;116(23):11428–11436. doi: 10.1073/pnas.1902651116

Fig. 3.

Fig. 3.

Alteration in PI3K and homologous recombination repair genes and association with clinical outcomes. (A) Oncoprint of genomic alterations in PI3K pathway genes. (B and C) Kaplan–Meier analysis showing overall survival (B) and time on treatment with a first-line ARSI (C) in PI3K pathway altered (red) versus unaltered (black) tumors. (D) Oncoprint of genomic alterations in BRCA2, BRCA1, and ATM. (E) Kaplan–Meier analysis showing time on treatment with a first-line ARSI in BRCA2/1/ATM–altered (homozygous deletion or somatic or pathogenic germline mutation) (red) versus unaltered (black) tumors.