Table 2.

Multivariate analysis evaluating the association of common genomic alterations with overall survival and time on treatment with first-line ARSI

Clinical outcome	Gene alteration(s)	Multivariate relative risk (95% CI for RR)
Overall survival from start of first-line ARSI	RB1−	1
	RB1+	3.31 (1.64, 6.67)
Time on treatment with first-line ARSI	RB1− and AR−	1
	RB1− and AR+	1.86 (1.18, 2.95)
	RB1+	6.56 (2.94, 14.62)

Common genomic alterations listed in Table 1 were included in this analysis. Only significant associations are shown. CI, confidence interval; RR, relative risk.