Table 1.
Regional [18F]FPEB VT and significance values across reported suicidal ideation in both PTSD and MDD groups
| Region | MDD-No SI, n = 14 | MDD-SI, n = 15 | PTSD-No SI, n = 15 | PTSD-SI, n = 14 | Cohen’s d (PTSD) | P value (PTSD) |
| dlPFC | 33.63 (6.04) | 33.84 (9.39) | 32.71 (6.80) | 43.18 (7.01) | 1.51 | 0.001 |
| vmPFC | 32.11 (5.64) | 32.34 (8.54) | 31.39 (6.59) | 40.81 (7.45) | 1.34 | 0.001 |
| OFC | 30.64 (5.32) | 30.60 (8.78) | 30.39 (6.21) | 38.46 (3.94) | 1.55 | 0.003 |
| Amygdala | 26.83 (4.93) | 27.23 (7.22) | 26.75 (5.38) | 32.93 (4.84) | 1.21 | 0.007 |
| Hippocampus | 24.62 (5.61) | 25.01 (6.01) | 24.49 (5.25) | 30.26 (5.15) | 1.11 | 0.004 |
Mean (SD) reported. dlPFC, dorsolateral prefrontal cortex; OFC, orbitofrontal cortex; vmPFC, ventromedial prefrontal cortex.