TABLE 2.
Operons associated with production of citramalic acid by an E. coli cell factory that were differentially regulated ≥2-fold (adjusted P value of ≤0.05) relative to control fermentationsa
| Gene or operon | Function | Fold change | Direction of regulation |
|---|---|---|---|
| trpLEDCBA | Tryptophan biosynthesis | 5.1 | Up |
| ygbJK | Hypothetical protein | 4.1 | Down |
| malK-lamB-malM | Maltose transport | 3.8 | Up |
| exuT | Hexuronate transport | 3.6 | Down |
| cysDNC | Sulfur metabolism | 3.1 | Up |
| cysPUWAM | Sulfur metabolism | 2.8 | Up |
| fliAZ-tcyJ | Flagellar biosynthesis | 2.6 | Up |
a
Fold change is for the first gene in the operon unless indicated otherwise by boldface type.