TABLE 1.
Dysregulated proteins involved in catabolic pathways
| GI no., descriptiona | Protein abundance ratiob
|
COG categoryc | |||
|---|---|---|---|---|---|
| UV-Space | UV-Mars | Dark-Space | Dark-Mars | ||
| Phosphoenolpyruvate-dependent sugar PTS | |||||
| 500860925, PTS β-glucoside transporter subunit EIIBCA | −0.689 | −1.311 | −1.243 | −0.787 | CTM |
| 500860804, PTS β-glucoside transporter subunit EIIBCA | −0.259 | −0.378 | −0.740 | −0.235 | CTM |
| 500860752, PTS fructose transporter subunit IIA | −0.046 | −0.509 | −0.831 | −0.705 | CTM |
| 500857289, PTS fructose transporter subunit IIB | −1.247 | −1.819 | −1.990 | −1.138 | CTM |
| 500857288, PTS fructose transporter subunit IIC | −0.556 | −0.483 | −1.493 | −0.717 | CTM |
| 500857290, PTS glucose transporter subunit IIA | −0.960 | −1.063 | −1.771 | −0.907 | CTM |
| 500860749, PTS lactose/cellobiose transporter subunit IIA | −0.381 | −0.294 | −0.873 | −0.442 | CTM |
| 500860751, PTS sugar transporter subunit IIB | −0.895 | −0.963 | −1.596 | −0.471 | CTM |
| 489303627, multispecies, phosphocarrier protein HPr | −0.506 | −1.019 | −0.887 | −0.451 | CTM |
| 494764325, multispecies, PTS sorbitol transporter subunit IIA | 0.140 | 0.480 | 1.205 | 0.173 | CTM |
| TCA cycle | |||||
| 500857502, α-ketoacid dehydrogenase subunit β* | −0.625 | −2.094 | −3.439 | −2.575 | EPC |
| 500858738, citrate synthase | 0.227 | −0.688 | −1.332 | −0.902 | EPC |
| 495621484, multispecies, citrate synthase | −0.125 | −0.775 | −1.589 | −0.990 | EPC |
| 500858752, 2-oxoglutarate dehydrogenase subunit E1 | −0.165 | −0.346 | −1.000 | −0.666 | EPC |
| 500858751, dihydrolipoyllysine-residue succinyltransferase | −0.362 | −0.676 | −1.264 | −0.810 | EPC |
| 489304636, multispecies, succinate-CoA ligase subunit α | −0.086 | −0.563 | −1.168 | −0.541 | EPC |
| 500858441, multispecies, succinyl-CoA ligase subunit β | 0.228 | −0.354 | −0.929 | −0.597 | EPC |
| 500857504, dihydrolipoyl dehydrogenase | −0.770 | −1.816 | −2.652 | −2.276 | EPC |
| 500859474, multispecies, phosphoenolpyruvate carboxykinase (ATP) | 0.375 | −0.832 | −1.788 | −0.960 | EPC |
| Electron transfer chains | |||||
| 489303411, cytochrome (ubi)quinol oxidase subunit III | −0.296 | −0.570 | −1.525 | −1.170 | EPC |
| 754202327, cytochrome c′ | 0.348 | −0.479 | −0.641 | −0.719 | EPC |
| 500858340, cytochrome c oxidase subunit I | 0.028 | −0.307 | −1.355 | −0.653 | EPC |
| 489304759, cytochrome c oxidase subunit II | −0.215 | −1.312 | −1.443 | −1.435 | EPC |
| 494765503, multispecies, menaquinol-cytochrome c reductase iron-sulfur subunit | 0.107 | −0.922 | −1.095 | −0.759 | EPC |
| 500859318, electron transfer flavoprotein subunit alpha/FixB family protein | −0.518 | −0.863 | −1.327 | −0.913 | EPC |
| 500859319, electron transfer flavoprotein subunit β* | −0.560 | −0.979 | −1.465 | −0.925 | EPC |
| 500858688, (Fe-S)-binding protein* | −0.639 | −0.931 | −1.140 | −1.195 | EPC |
| 754202216, NADH-dependent flavin oxidoreductase | −0.950 | −0.626 | −0.749 | −0.673 | EPC |
| Fatty acid beta-oxidation | |||||
| 500859322, long-chain fatty acid-CoA ligase | −0.062 | −0.677 | −1.386 | −0.756 | LTM |
| 500859693, 3-hydroxyacyl-CoA dehydrogenase | −0.281 | −0.685 | −1.361 | −0.736 | LTM |
a
*, P ≤ 0.05 (one-way ANOVA).
b
The values shown represent protein abundance ratios (log2) normalized to the ground control.
c
CTM, carbohydrate transport and metabolism; EPC, energy production and conversion; LTM, lipid transport and metabolism.