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. Author manuscript; available in PMC: 2019 Dec 5.
Published in final edited form as: Org Biomol Chem. 2018 Dec 5;16(47):9171–9184. doi: 10.1039/c8ob02609b

Fig. 2.

Fig. 2

Representative time-activity curves of microPET studies for [18F]10a, [18F]17a, [18F]17b and (±)-[18F]24 in brains of nonhuman primates. The curves indicated that three radiotracers [18F]10a, [18F]17a and[18F]17b achieved the max SUV value fast, at 4–6 min post injection. [18F]10a had the highest initial brain uptake while [18F]17b exhibited relatively slow washout kinetics. (±)-[18F]24 displayed the lowest initial uptake in the brain, indicating it has no capability in penetrating the BBB of nonhuman primate.