Table 3.
fMRI Time Series Activation Interactions for Cannabis Group at Baseline, at Follow-up, and Between Visits
| Region | BA | No. of Voxels | F Value (Peak) | MNI-152 Coordinates at Peak | ||
|---|---|---|---|---|---|---|
| X | Y | Z | ||||
| Baseline | ||||||
| R lingual gyrus (A) | 18 | 57 | 5.79 | −1.5 | 79.5 | 1.5 |
| L lingual gyrus | 18 | 35 | 6.33 | 10.5 | 79.5 | −7.5 |
| L precuneus | 19 | 18 | 4.75 | 28.5 | 76.5 | 37.5 |
| L MFG | 6 | 17 | 5.11 | 28.5 | −10.5 | 64.5 |
| L IPL | 40 | 15 | 4.22 | 40.5 | 55.5 | 52.5 |
| R MFG | 6 | 15 | 4.10 | −13.5 | −7.5 | 70.5 |
| Paracentral lobule/cingulate gyrus | 31/7 | 14 | 4.65 | −10.5 | 34.5 | 49.5 |
| Pre-SMA | 8 | 14 | 5.60 | −1.5 | −19.5 | 55.5 |
| R lingual gyrus (B) | 18 | 13 | 4.28 | −34.5 | 67.5 | −7.5 |
| L lateral occipital gyrus (A) | 19 | 12 | 3.68 | 52.5 | 76.5 | 7.5 |
| L lateral occipital gyrus (B) | 19 | 12 | 5.37 | 40.5 | 88.5 | 7.5 |
| Follow-up | ||||||
| R cuneus (A) | 19 | 16 | 4.67 | −7.5 | 88.5 | 31.5 |
| R cuneus (B) | 23 | 12 | 4.88 | −4.5 | 73.5 | 7.5 |
| R cuneus (C) | 19 | 11 | 4.32 | −19.5 | 91.5 | 28.5 |
| Visit by Group | ||||||
| Posterior cingulatea | 31 | 11 | 4.93 | 1.5 | 58.5 | 25.5 |
F value cluster peak test statistic for group by time step (TR) interaction (baseline F14,1148; follow-up F14,896; visit by group F14,882). (A), (B), and (C) designations are used to distinguish clusters within the same region. Region and BA taken from a consensus among AFNI atlases (MNI and TT_Daemon).
BA, Brodmann area; fMRI, functional magnetic resonance imaging; IPL, inferior parietal lobule; L, left; MFG, middle frontal gyrus; MNI, Montreal Neurological Institute; R, right; SMA, supplementary motor area.
a
Estimates based on the longitudinal sample only.