Table 1.

ISGLS Definition and Grading of bile leakage after hepatobiliary surgery

Definition
Bile leakage is defined as fluid with an increased bilirubin concentration in the abdominal drain or in the intra-abdominal fluid on or after postoperative day 3 or as the need for radiological intervention because of biliary collections or relaparotomy resulting from bile peritonitis. Increased bilirubin concentration in the drain or intra-abdominal fluid is defined as a bilirubin concentration at least three times greater than the serum bilirubin concentration measured at the same time.
Grade
A	Bile leakage requiring no or little change in patients’ clinical management
B	Bile leakage requiring a change in patients clinical management (eg, additional diagnostic or interventional procedures) but manageable without relaparotomy or a Grade A bile leakage lasting for >1 week
C	Bile leakage requiring relaparotomy

ISGLS, International Study Group of Liver Surgery.