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. 2019 Jun 12;14(6):e0216139. doi: 10.1371/journal.pone.0216139

Fig 2. Suppression of ISGs expression after knockdown of IFNAR2.

Fig 2

HCV replicon cells were treated with IFNAR2 siRNA for 2 days and incubated with CDM-3008 for 8 h. (A) IFNAR1 expression after control and IFNAR2 siRNA treatment. IFNAR1 expression was not suppressed by IFNAR2 siRNA treatment. (B) IFNAR2 expression after control and IFNAR2 siRNA treatment. IFNAR2 mRNA expression was suppressed by treatment with IFNAR2 siRNA but not by treatment with control siRNA. (C) OAS1 expression after control and IFNAR2 siRNA treatment. OAS1 mRNA expression was suppressed by treatment with IFNAR2 siRNA but not by treatment with control siRNA. The error bars in A-C indicate S.D. (n = 3). *, p < 0.05; **, p < 0.01 (two-tailed t-test) in A-C.