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. 2019 Jun 12;14(6):e0216139. doi: 10.1371/journal.pone.0216139

Fig 3. Analysis of anti-HBV activity in HepG2-derived cells.

Fig 3

(A) Schematic experimental design of the anti-HBV activity analysis. Hep38.7-Tet cells were cultured for 1 day; the cells were then treated with 0–100 μM CDM-3008 for 6 days (magenta). The black triangles show the times at which the medium was changed. (B, C) Hep38.7-Tet cells were treated with serially diluted CDM-3008 (0–100 μM) for 6 days. After 6 days of treatment, the HBV DNA levels in the cell culture medium were measured by qPCR (B), and cell viability was measured by XTT assay (C). The error bars in B, C indicate S.D. (n = 3).