Fig 10. Additive effect of CDM-3008 and entecavir on anti-HBV activity.
Primary cultured human hepatocytes (PXB cells) were infected with HBV genotype C for 1day and cultured for 28 days; the cells were then treated with 0.1 μM CDM-3008 and/or 0.1 nM entecavir (ETV) for 7 days. HBV DNA copies in PXB cells were measured by qPCR. The error bars indicate S.D. (n = 3). *, p < 0.05 (two-tailed t-test).