Skip to main content
. 2019 Jun 12;14(6):e0212603. doi: 10.1371/journal.pone.0212603

Table 3. Findings from systematic reviews.

First author, year Health area specified Type(s) of interventions Findings Meta-analysis results
Table 3a. Findings from systematic reviews on asthma interventions
Geryk, 2017 [31] Asthma Education Improved inhaler technique n/a
Walter, 2016 [37] Asthma Education Improved daytime and nighttime symptoms; physical activity intolerance; emergency hospital visits; and missed school or work days n/a
Table 3b. Findings from systematic reviews on menstrual management interventions
Hennegan, 2016 [22] Menstruation Education, provision of sanitary products Sanitary pad provision: moderate yet statistically insignificant effect on school attendance; overall trends toward improvements in menstruation knowledge, management practices, psychosocial outcomes, and school attendance School attendance: SMD = 0.49, 95% CI = [-0.13, 1.11], p = 0.12
Table 3c. Findings from systematic reviews on mental health interventions
Bastounis, 2016 [19] Depression and anxiety Education, prevention Depression: non-significant, in favor of PRP program;
Anxiety: non-significant, in favor of control
Depression: MD = -0.23, 95% CI = [-1.09, 0.62]
Anxiety: SMD = 0.13 95% CI = [0.00, 0.26]
Brendel, 2014 [29] Well-being Counseling No statistically significant change n/a
Gold, 2006 [23] Autism Therapy (music) Small yet statistically significant effect sizes in favor of music therapy Gestural communication: SMD = 0.50, 95% CI = [0.22, 0.79]*
Verbal communication: SMD = 0.36, 95% CI = [0.15, 0.57]*
Behavioral problems: S*
Higgins, 2015 [32] Anxiety Prevention Statistically significant improvement in self-reported anxiety n/a
Kavanagh, 2009 [24,39] Depression and anxiety Counseling Statistically significant reductions of depressive symptoms up to four weeks and three months follow-up 4 weeks: SMD = -0.16, 95% CI = [-0.26, -0.05]; Equivalent to reduction in 1.44 points on BDI*
3 months: SMD = -0.21, 95% CI = [-0.35, -0.07]; equivalent to reduction in 1.9 points on BDI*
McDonald, 2018 [33] Various Therapy (art) Improvements in outcomes on classroom behavior, ODD, and SAD n/a
Neil, 2009 [34] Anxiety Prevention Statistically significant reductions in anxiety symptoms at post-test and/or follow-up in 21 out of 27 primary trials n/a
Sullivan, 2016 [36] Trauma Therapy Improvements in trauma-related symptoms and impairment; negative effects for music therapy n/a
Werner-Seidler, 2017 [28] Depression and anxiety Prevention, therapy Small yet statistically significant effect sizes in favor of the intervention for both depression and anxiety Depression: Hedges g = 0.23, 95% CI = [0.19, 0.28]*
Anxiety: Hedges g = 0.20, 95% CI = [0.14, 0.25]*
Table 3d. Findings from systematic reviews on obesity interventions
Schroeder, 2016 [26] Obesity prevention and treatment Education, counseling, prevention Small but statistically significant reductions in all three BMI outcomes BMI, attenuated due to high heterogeneity: SMD = -0.06, 95% CI = [-0.17, -0.01]*
BMIz score: SMD = -0.10, 95% CI = [-0.15, -0.05]*
BMI percentile: SMD = -0.41, 95% CI = [-0.60, -0.21]*
Table 3e. Findings from systematic reviews on oral health interventions
Arora, 2017 [18] Oral health and dental care attendance Screening, referrals Insufficient evidence for conclusions on oral health outcomes or dental attendance n/a
Cooper, 2013 [30] Caries Education, prevention Insufficient evidence for conclusions on caries increment or plaque accumulation n/a
Marinho, 2015 [25] Caries Prevention Decrease in caries increment PF = 0.28, 95% CI = [0.19, 0.36], p < 0.0001*
Stein, 2017 [27] Caries and oral hygiene Education Decrease in mean plaque levels; improved oral hygiene; no change in gingivitis Mean plaque levels: MD = -0.36 95% CI = [-0.59, -0.13], p = 0.004*
Oral hygiene: MD = -0.42, 95% CI = [-0.69, -0.15], p = 0.002*
Gingivitis: MD = -0.07, 95% CI = [-0.32, 0.19], p = 0.61
Table 3f. Findings from systematic reviews on sexual and reproductive health interventions
Paul-Ebhohimhen, 2008 [35] STIs and HIV Education Increased knowledge and attitudes; ineffective in changing risky behaviors n/a
Table 3g. Findings from systematic reviews on sleep interventions
Chung, 2017 [20] Sleep Education Statistically significant short-term benefits for all three outcomes Weekday sleep time: SMD = 0.23, 95% CI = [0.17, 0.29], p = 0.0001*
Weekend sleep time: SMD = 0.46, 95% CI = [0.04, 0.86], p = 0.03*
Mood: SMD = 0.81, 95% CI = [0.17, 1.47], p = 0.01*
Table 3h. Findings from systematic reviews on vision interventions
Evans, 2018 [21] Visual acuity Education, screening, spectacles provision Statistically significant increase in spectacles wear; no difference between provision of ready-made vs. custom-made spectacles; no comparison of vision screening vs. no vision screening Free spectacles vs. prescription: RR = 1.6, 95% CI = [1.34, 1.90], p <0.00001*
Ready-made vs. custom-made: RR = 0.98, 95% CI = [0.91, 1.05], p = 0.51

n/a = no meta-analysis performed; MD = mean difference; SMD = standardized mean difference; PF = prevented fraction; RR = risk ratio; BDI = Beck Depression Inventory; ODD = Oppositional Defiant Disorder; SAD = Separation Anxiety Disorder; BMI = body mass index; PRP = Penn Resiliency Program; HIV = human immunodeficiency virus; STI = sexually transmitted infection

* = statistically significant result; CI = 95% confidence interval; p = p-value