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. 2019 Jun 12;14(6):e0217597. doi: 10.1371/journal.pone.0217597

Table 4. The 4 predominant patterns in drug-resistant culture positive TB cases with DST results, by country of birth and age group (for cases with available information), Germany 2008–2017, Isoniazid (H), Rifampicin (R), Pyrazinamide (Z), Ethambutol (E), and Streptomycin (S).

Age group: < 15 yr.
Country of birth Total No. of TB cases Any resistance present Among any resistance
H Z S HS
Germany 366 64 (17.5%) 16 (25.0%) 6 (9.4%) 20 (31.3%) 12 (18.8%)
Other 209 39 (18.7%) 9 (23.1%) 6 (15.4%) 7 (17.9%) 5 (12.8%)
Total 575 103 (17.9%) 25 (24.3%) 12 (11.7%) 27 (26.2%) 17 (16.5%)
Age group: 15–39 yr.
Total No. of TB cases Any resistance present Among any resistance
H Z S HS
Germany 1,979 167 (8.4%) 50 (29.9%) 10 (6.0%) 54 (32.3%) 24 (14.4%)
Other 8,323 1,381 (16.6%) 302 (21.9%) 101 (7.3%) 354 (25.6%) 218 (15.8%)
Total 10,302 1,548 (15.0%) 352 (22.7%) 111 (7.2%) 408 (26.4%) 242 (15.6%)
Age group: 40–59 yr.
Total No. of TB cases Any resistance present Among any resistance
H Z S HS
Germany 3,449 287 (8.3%) 71 (24.7%) 45 (15.7%) 76 (26.5%) 45 (15.7%)
Other 3,542 633 (17.9%) 132 (20.9%) 46 (7.3%) 139 (22.0%) 150 (23.7%)
Total 6,991 920 (13.2%) 203 (22.1%) 91 (9.9%) 215 (23.4%) 195 (21.2%)
Age group: 60+ yr.
Total No. of TB cases Any resistance present Among any resistance
H Z S HS
Germany 5,174 395 (7.6%) 91 (23.0%) 145 (36.7%) 86 (21.8%) 18 (4.6%)
Other 2,525 283 (11.2%) 78 (27.6%) 44 (15.5%) 61 (21.6%) 56 (19.8%)
Total 7,699 678 (8.8%) 169 (24.9%) 189 (27.9%) 147 (21.7%) 74 (10.9%)
All age groups
Total No. of TB cases Any resistance present Among any resistance
H Z S HS
Germany 10,969 913 (8.3%) 228 (24.9%) 206 (22.6%) 236 (25.8%) 99 (10.8%)
Other 14,600 2,336 (16.0%) 521 (22.3%) 197 (8.4%) 561 (24.0%) 429 (18.4%)
Total 25,569 3,249 (12.7%) 749 (23.1%) 403 (12.4%) 797 (24.5%) 528 (16.3%)