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. 2019 Jun 12;14(6):e0218085. doi: 10.1371/journal.pone.0218085

Table 4. Enriched KEGG-terms from the shared freshwater eel branch of Fig 4.

KEGG ID Term Annotated Significant Expected FDR
04728 Dopaminergic synapse 38 283 12 0,000001
03015 mRNA surveillance pathway 21 129 5 0,000082
04660 T cell receptor signaling pathway 27 204 8 0,000082
04071 Sphingolipid signaling pathway 29 238 10 0,000112
05142 Chagas disease (American trypanosomiasis) 23 180 7 0,000518
04659 Th17 cell differentiation 23 184 7 0,000596
05162 Measles 21 168 7 0,001190
04390 Hippo signaling pathway 29 282 11 0,001190
04658 Th1 and Th2 cell differentiation 19 148 6 0,001601
04261 Adrenergic signaling in cardiomyocytes 28 291 12 0,004378
05100 Bacterial invasion of epithelial cells 20 183 7 0,005845
05032 Morphine addiction 18 155 6 0,005845
00625 Chloroalkane and chloroalkene degradation 5 10 0 0,005845
04640 Hematopoietic cell lineage 12 79 3 0,006536
04910 Insulin signaling pathway 26 276 11 0,006551
04630 Jak-STAT signaling pathway 18 171 7 0,012920
04016 MAPK signaling pathway—plant 6 22 1 0,014553
04022 cGMP-PKG signaling pathway 29 350 14 0,015915
04917 Prolactin signaling pathway 15 133 5 0,015915
05130 Pathogenic Escherichia coli infection 13 108 4 0,019059
05418 Fluid shear stress and atherosclerosis 22 245 10 0,022738
00020 Citrate cycle (TCA cycle) 8 47 2 0,022808
04080 Neuroactive ligand-receptor interaction 31 395 16 0,023393
04151 PI3K-Akt signaling pathway 37 499 20 0,023393
04514 Cell adhesion molecules (CAMs) 21 231 9 0,023393
04391 Hippo signaling pathway—fly 16 158 6 0,034750
05340 Primary immunodeficiency 7 41 2 0,036069
04350 TGF-beta signaling pathway 16 164 7 0,038388
05133 Pertussis 12 111 5 0,045104
05152 Tuberculosis 21 247 10 0,047421
04664 Fc epsilon RI signaling pathway 12 113 5 0,048089
00510 N-Glycan biosynthesis 9 71 3 0,048943
04144 Endocytosis 37 533 22 0,048943
00350 Tyrosine metabolism 6 34 1 0,048943
04510 Focal adhesion 28 379 15 0,048943

Enriched KEGG-terms from the duplicated genes shared by freshwater eels. “KEGG ID” indicates the identification number of each enriched KEGG pathway. “Term”indicates the verbal description of each enriched KEGG pathway. “Annotated” indicates the number of KEGG pathways, which are associated with each enriched KEGG pathway. “Significant” indicates the number of KEGG pathways associated with each enriched KEGG pathway found among the duplicated genes. “Expected” indicates the number of KEGG pathways expected to be found associated with each enriched KEGG pathway. “FDR” indicates the False Discovery Rate adjusted P-value from the Fisher exact test of enrichment.