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. 2019 May 2;55(1):131–141. doi: 10.3892/ijo.2019.4792

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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BDKRB2 is overexpressed in cervical cancer tissues. (A) BDKRB2 was significantly upregulated in CC vs. normal samples in one dataset (Scotto Cervix Statistics) of the Oncomine online database (P<0.05). (B) The overexpression of BDKRB2 was further verified in CC tissues (n=15) and normal cervical tissues (n=9) by RT-qPCR (P<0.05). (C) Typical IHC images of BDKRB2 in CC, CIN and normal tissues. (D) The relevant cartogram of IHC scores of CC (n=44), CIN (n=12) and CON (n=8) tissues. BDKRB2 was notably overexpressed in CC (P<0.05) and CIN tissues (P<0.05) compared to normal cervical tissues. ^*P<0.05. n.s. non-statistical significance; BDKRB2, bradykinin B2 receptor; CC, cervical cancer; CIN, cervical intraepithelial neoplasia; NC, normal control.