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. 2019 Jun 12;14(6):e0216776. doi: 10.1371/journal.pone.0216776

Fig 1. Schematic drawing of layer-by-layer UV-assisted bioprinting strategy.

Fig 1

The gellam gun in the bio-ink serves as a viscosity enhancer to improve the bio-ink printability (via formation of ionic bonds between GelMA chain and gellan gum) during the extrusion printing process prior to further UV crosslinking (to form chemical bond between adjacent GelMA chains) of each individual printed layer. This layer-by-layer UV-assisted bioprinting strategy is repeated to eventually achieve fabrication of complex 3D structures with high aspect ratio.