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. Author manuscript; available in PMC: 2019 Sep 8.
Published in final edited form as: J Perinatol. 2019 Mar 8;39(5):599–607. doi: 10.1038/s41372-019-0347-4

Table 2:

Adjusted relative risk and 95% confidence interval of the relationships between the individual treatment groups and ductus constriction. The potential confounders in the model were: gestational age (<26 0/7 weeks or ≥26 0/7 weeks), antenatal betamethasone exposure (<24 hours or ≥24 hours), and Caucasian race (yes or no).

Relative Risk 95% CI p-value a
Treatment Group
Conservative 1.0
Acetaminophen 1.33 (0.55 – 3.24)
Ibuprofen 2.03 (1.05 – 3.91) 0.035
Indomethacin 3.21 (2.05 – 5.01) <0.001
Gestation ≥26 0/7 weeks 1.21 (0.85 – 1.70)
Betamethasone ≥24 hours 0.78 (0.58 – 1.05)
Caucasian 1.14 (0.75 – 1.74)
a,

p-value are presented only for values ≤0.10