Table 2:
Risk of bias assessment in individual randomised controlled trials
| Random sequence generation | Allocation concealment | Blinding of clinicians and data collectors | Blinding of outcome assessors | Incomplete outcome data (for clinicians) | Selective outcome reporting | Other sources of bias | |
|---|---|---|---|---|---|---|---|
| Coylewright 201613 and 201714 (nested study) | low | low | high | unclear/ not reported | high | high | low |
| Hess 201615 | low | low | high | low | low | high | high |
| Hess 201216 | low | low | high | low | low | high | high |
| Perestelo-Pérez 201617 | low | unclear/ not reported | high | unclear/ not reported | low | low | low |
| Nannenga 200918 | low | low | high | low | low | low | low |
| Thomson 200719 | low | low | high | unclear/ not reported | low | low | low |
| Warner 201520 | low | unclear/ not reported | high | unclear/ not reported | low | low | low |
| Mathers 201221 | low | low | high | high | low | low | low |
| Karagiannis 201623 | low | low | high | unclear/ not reported | low | low | low |
| Mullan 200924 | low | low | high | unclear/ not reported | low | low | low |
| Denig 201425 | low | low | high | unclear/ not reported | low | low | low |
| LeBlanc 2015 Osteoporosis26 | low | low | high | high | unclear/ not reported | low | high |
| Montori 201127 | low | low | high | low | low | low | low |
| LeBlanc2015 Depression28 | low | unclear/ not reported | high | unclear/ not reported | low | low | low |
| Loh 200729 | low | low | high | unclear/ not reported | unclear/ not reported | low | low |
| Légaré 201230 | low | low | high | low | low | low | low |
| Légaré 201131 | low | low | high | low | low | low | low |
| Little 201539 (parent study of Anthierens 201432) |
low | low | high | unclear/ not reported | low | low | low |
| Walczak 201733 | low | low | high | unclear/ not reported | high | high | high |
| Leighl 201134 | low | low | high | unclear/ not reported | low | low | low |
| Ozanne 200735 | unclear/ not reported | unclear/ not reported | high | unclear/ not reported | low | low | high |
| Whelan 200336 | low | unclear/ not reported | high | unclear/ not reported | unclear/ not reported | unclear/ not reported | low |
| Bekker 200437 | low | low | high | high | low | low | low |
low: low risk of bias (green)
unclear/not reported: risk of bias was unclear or not reported (yellow)
high: high risk of bias (red)