Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jun 12;5(6):eaaw1327. doi: 10.1126/sciadv.aaw1327

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license, which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.

PMC Copyright notice

Fig. 5 — Treatment with 30 μg of three different clones of anti-CotH3 monoclonal antibodies (mAb) (C1 to C3), 24 hours after intratracheal R. delemar infection, protected DKA mice (n = 9 to 10 mice per group) (A) and neutropenic mice (n = 10 to 15 per group) (B) from lethal mucormycosis. *P < 0.05 versus isotype-matched control IgG; **P < 0.05 versus isotype-matched control IgG, C1 clone, and polyclonal IgG. C2 clone also protected neutropenic mice from mucormycosis due to M. circinelloides (C) and L. corymbifera (D). n = 10 per group for mice in (C) and (D). Confirmed inhaled inocula were 5.6 × 10³, 2.2 × 10³, 1.6 × 10³, and 2.1 × 10³ for (A) to (D), respectively.