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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Respir Physiol Neurobiol. 2019 May 3;266:54–65. doi: 10.1016/j.resp.2019.04.014

Fig. 5. Long-lasting effects of intermittent SubP application on burst frequency and amplitude in pontine brainstem-spinal cords.

Fig. 5.

(A) The time course of burst frequency effects are shown for intermittent SubP application (3-min application/7-min washout, ×3) at 10 nM (gray circles) and 100 nM (black circles). Data from time control experiments are shown (white squares). Intermittent SubP applications induced frequency plasticity at 100 nM, but not at 10 nM. (B) Mean percent change in burst frequency at the 90-min time point is shown for males (white circles) and females (white squares) following 0 nM SubP (time controls) and 100 nM SubP intermittent applications. Individual data points in each group are shown as black circles. There were no sex-dependent differences in frequency plasticity. (C) The time course of burst amplitude effects are shown for intermittent SubP applications. There were no long-lasting decreases in burst amplitude following intermittent 100 and 10 nM SubP applications compared to time controls. Statistics symbols as in Fig. 2 legend.