Table 1:
Sample demographics and clinical characteristics
| HC (N) |
MDD with No Suicidal Ideation (N) |
MDD with Suicidal Ideation (N) |
MDD NSI vs. MDD SI p-value |
Three Group Comparison p-value |
|
|---|---|---|---|---|---|
| Sex (% female) | 61.84 | 60.00 | 57.14 | 0.817 | 0.910 |
| BMI (kg/m2; M±SD) | 24.44±4.58 (76) |
26.21±4.95 (40) |
25.08±3.80 (28) | 0.290 | 0.140 |
| Age (years; M±SD) | 37.16±13.29 (76) |
38.33±14.75 (40) |
40.04±12.54(28) | 0.619 | 0.625 |
| Years of Education (M±SD) | 16.74±1.81 (76) |
16.13±2.21 (40) |
16.25±2.3 (28) | 0.822 | 0.250 |
| Smoking status (% smoking) | 7 (9.2) | 9 (22.5) | 8 (27.6) | 0.628 | 0.038* |
| Platelet count (M±SD) | 225.24±46.9 3 (71) | 215.79±54.57 (39) |
204.44±60.75 (27) |
0.431 | 0.200 |
| PSS score (M±SD) | 8.88±4.68 (76) |
22.89±6.98 (38) |
26.60±7.44 (25) | 0.049* | <0.001* |
| HDRS-17 score (M+SD) | - | 19.13±2.27 (40) | 21.36±3.99 (28) | 0.005* | - |
| Lifetime Depression Chronicity (months; adjusted; M±SD) | - | 106.95±102.94 (40) |
140.13±130.04 (27) |
0.249 | - |
| BDNF (z-scores) | −.08+.97 (75) |
.34±1.07 (40) | −.26±.82 (28) | .016 | .029 |
| YPAS (frequency x duration) | 4.86±3.14 (71) |
3.21±3.74 (38) |
2.90±3.23 (29) |
0.719 | 0.008* |
*
Significant at the p<0.05 level.
BMI: Body Mass Index, PSS: Perceived Stress Score, HDRS-17: 17 item Hamilton Depressive Rating Scale, YPAS: Yale Physical Activities Scale