Table 2:

Clinical information and family history of cancer

ID	Age	Race	Sex	CRC Locationa	Family History of Cancer
LS: MMR germline mutation
1	68	WEA	F	R and L	Mother: breast Father: renal cell
2	27	WEA	M	R	Great grandmother: colon Grandmother: colon, uterus Great grand uncle: colon Aunt: colon, pancreas Cousin: colon
3	78	AA	M	L	n/a
4	62	WEA	F	L	n/a
5b	55	AA	F	R	Aunt: breast
LLS: No MMR germline mutations
6	67	AA	M	n/a	n/a
7	53	WEA	M	R	Mother: breast Father: prostate
8	70	AA	F	R	Brother: esophagus
9	65	AA	F	R	Father and brother: prostate Sister: breast Brother: renal cell Aunt: neck
10	46	AA	F	n/a	n/a
11	86	AA	M	R	Father: brain
12	81	AA	F	R	Mother: Uterus
13	47	WEA	M	R	n/a
14	77	AA	M	R	n/a
15	58	WEA	M	L	n/a
16	50	WEA	F	L	Mother: brain Brother: colon

AA, African American; CRC, colorectal cancer; F, female; LLS, Lynch-like syndrome; LS, Lynch syndrome; M, male; n/a: not available, no information; WEA, White European American.

^aTumor location is divided into tumors in the proximal colon, including the cecum, ascending colon, hepatic flexure, and transverse colon (R, right), and tumor in the distal colorectum, including the splenic flexure, descending colon, sigmoid colon, and rectum.

^bThis case was seen in the University of Illinois at Chicago Familial Cancer Genetics Clinic, where she was found to have a LS mutation