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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Psychiatry Clin Neurosci. 2019 Mar 28;73(6):323–330. doi: 10.1111/pcn.12835

Table 2. Subject and sample characteristics of the neurosurgery study participants.

Sample tissues available for each individual varied. Details of analyzed samples are shown. Timing of when peripheral tissues were obtained are listed as “days”. Day 0 is indicative of samples taken the day of surgery, after surgery is completed. For brain samples analyzed, the time (in minutes) between administration of the synthetic glucocorticoid and when the second (post) brain sample was resected was recorded. Abbreviations. GC: glucocorticoid, FCD: focal cortical dysplasia.

      Day(s) after surgery for peripheral sample collection    
Subject Sex Age Saliva Blood Buccal Brain region (pre) Brain region (post) GC duration (minutes) Pathology report (pre) Pathology report (post)
101 female 50 638        
102 female 46 309        
103 female 31 362 2      
104 female 51 263 0      
105 female 28 222 0      
106 male 61 2 0      
107 male 43 198 0      
108 male 40 241 0      
109 male 7 23 0 23 Occipital area Occipital area 180 FCD type Ic and gliosis Same as pre-GC sample
110 male 17 3 0 3 Inferior lateral temporal cortex Inferior lateral temporal cortex 38 Evidence of cortical dysplasia, focal meningitis, and cortical injury consistent with electrode placement Same as pre-GC sample
111 female 14 3 0 3  
112 male 31 2 0 2  
113 male 36 2 0 2 Temporal cortex Temporal cortex 100 Moderate, patchy gliosis, and multiple superficial subacute microinfarcts with adjacent leptomeningeal chronic inflammation consistent with history of previous dural grid placement Same as pre-GC sample
114 male 30 3 0 3 Lateral temporal cortex Lateral temporal cortex 130 Patchy mild gliosis Same as pre-GC sample
115 male 24 2 0 2 Lateral temporal cortex Hippocampus 90 Mild neuronal heterotopia and mild patchy gliosis Hippocampal sclerosis and moderate patchy gliosis
116 male 34 2 0 2 Lateral temporal cortex Lateral temporal cortex 130 Patchy moderate gliosis and focal meningitis secondary to electrode placement Same as pre-GC sample
117 female 49 2 0 2 Lateral temporal cortex Inferior lateral temporal cortex 100 FCD type Ic and white matter gliosis Subpial and white matter gliosis
118 male 5 4 0 4  
119 male 38 2 0 2 Lateral temporal cortex Hippocampus 64 White matter and cortical gliosis and subacute infarct Hippocampal sclerosis
120 male 11 122 0 14 Temporal operculum Temporal operculum 152 Mild neuronal disorganization with white matter and cortical gliosis Same as pre-GC sample
121 male 5 4 0 4 Temporal pole Temporal pole 32 FCD Same as pre-GC sample