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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Hypertension. 2019 May 20;74(1):173–183. doi: 10.1161/HYPERTENSIONAHA.119.13101

Figure 3. Endothelial Function in Adult Offspring: Role of ROS.

Figure 3.

A-B) Cumulative concentration response curves for ACh in carotid arteries with and without tempol (1mmol/L, 30 mins) in male (A) and female (B) offspring from the indicated pregnancy. S, saline; T, Tempol. Data are presented as mean±SEM analyzed by two-way ANOVA with repeated measures. *P<0.05 vs. E-V290M AVP + Tempol and Saline + Tempol. C-D) Representative western blots showing expression levels of Nrf2 and NQO1 in the aorta and its quantification from Ang-II-treated adult male (C) and female (D) NT and E-V290M offspring born from SAL or AVP-infused pregnancies (n=5–6 per group). Actual size markers transferred from the blots are shown. Data from the entire experiment are shown in the graphs. Data are presented as mean±SEM analyzed by two-way ANOVA. *P<0.05 vs. E-V290M SAL, $P<0.05 vs. NT AVP.