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. 2019 Jun 12;9:8564. doi: 10.1038/s41598-019-45089-z

Figure 1.

Figure 1

Age-dependent comparative transcriptomic analysis of the peripheral whole blood. (a) Heat map of top 30 genes significantly upregulated in the juvenile whole blood at 4d post-CCI injury compared to juvenile sham. (b) Identification of Genes upregulated in the adult CCI-injured whole blood compared to sham injury. (c) Comparison of genes upregulated following CCI injury in juvenile vs adult whole blood. No upregulated genes were found to overlap. (d) Downregulated genes in juvenile CCI-injured and in (e) adult whole blood compared to respective shams. (f) No downregulated genes were found to overlap. (gi) Comparison of genes found to be significantly increased or reduced in sham juvenile compared to sham adult. (j) Genes that were increased in juvenile sham vs adult sham that were also increased in juvenile CCI vs adult CCI samples. (k) Genes that were decreased in juvenile sham vs adult sham that were also increased in juvenile CCI vs adult CCI samples.