Table 3.
Univariable and multivariable logistic regression analysis with generalized estimating equation to determine clinical variables associated with overall visual field progression.
| POAG | Univariable | Multivariable | ||||
|---|---|---|---|---|---|---|
| Exp(B) | 95% CI | P value | Exp(B) | 95% CI | P value | |
| Age (year) | 0.997 | 0.961 to 1.034 | 0.855 | |||
| Gender | 0.583 | 0.232 to 1.466 | 0.251 | |||
| Baseline IOP | 0.971 | 0.807 to 1.169 | 0.755 | |||
| Mean F/U IOP | 1.020 | 0.755 to 1.379 | 0.896 | |||
| Peak F/U IOP | 1.000 | 0.796 to 1.256 | 0.999 | |||
| F/U IOP fluctuation | 0.924 | 0.691 to 1.235 | 0.835 | |||
| CCT (µm) | 1.005 | 0.991 to 1.020 | 0.493 | |||
| CMvD | 4.216 | 1.654 to 10.746 | 0.003* | 3.573 | 1.023 to 12.482 | 0.046* |
| DH | 12.442 | 3.704 to 41.799 | <0.001* | 15.176 | 3.708 to 62.107 | <0.001* |
| Baseline MD | 0.945 | 0.744 to 1.270 | 0.665 | |||
| SE | 0.896 | 0.756 to 1.137 | 0.268 | |||
| β-PPA/disc area | 1.507 | 1.218 to 1.864 | <0.001* | 1.428 | 1.116 to 1.829 | 0.005* |
| F/U period | 1.201 | 1.018 to 0.994 | 0.136 | |||
*P < 0.05 in univariable and multivariable logistic regression analysis with generalized estimating equation (GEE). A GEE model was used to adjust for potential inter-eye associations of the same patients.
Abbreviations: IOP, intraocular pressure; CCT, central corneal thickness; AL, axial length; CMvD, choroidal microvasculature dropout; DH, disc hemorrhage; MD, mean deviation; SE, spherical equivalent; β-PPA, β-zone parapapillary atrophy; F/U, follow-up.