Table 4.

Comparison of parapapillary retinal nerve fiber layer (RNFL) and macular ganglion cell inner plexiform layer (GCIPL) thickness progression rates and frequency of progression based on the GPA software of eyes with open-angle glaucoma with (CMvD+) and without (CMvD−) CMvD.

GPA progression rate	CMvD(−), n = 30	CMvD(+), n = 33	P value
RNFL GPA progression rate, µm/yr
Average	−0.39 ± 0.59	−0.80 ± 0.66	0.009*
Superior quadrant	−0.52 ± 1.02	−1.18 ± 1.11	0.020*
Inferior quadrant	−1.06 ± 1.19	−1.45 ± 1.26	0.219
RNFL progression, n (%)†	7 (23.3%)	22 (66.7%)	0.001*
GCIPL progression rate, µm/yr
Average	−0.40 ± 0.38	−0.72 ± 0.51	0.009*
Superior hemifield	−0.38 ± 0.42	−0.59 ± 0.51	0.091
Inferior hemifield	−0.44 ± 0.49	−0.90 ± 0.89	0.016*
GCIPL progression, n (%)†	3 (10.7%)	16 (48.5%)	0.002*

Data are reported as mean ± standard deviation or n (%). *P < 0.05 by independent t-tests unless otherwise indicated. ^†Chi-squared tests.

Abbreviations: CMvD, choroidal microvasculature dropout; n, number; RNFL, retinal nerve fiber layer; GCIPL, ganglion cell inner plexiform layer; GPA, guided progression analysis.