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. 2019 Jun 12;9:8528. doi: 10.1038/s41598-019-44562-z

Table 3.

Top images features discriminating cancer and benign nodules using image features across categories.

All Categories (129 Reproducible, Non-Redundant Features)
Features Training Testing
Broad description Detailed feature Image Image + Clinical Image Image + Clinical
E[AUC], CI E[AUC], CI E[AUC], CI AUC
Size, Shape and Texture (F3: ShortAx; F4: Mn-Hu; F26: EllipticFit; F176: 3D-Laws-127) 0.83 [0.71, 0.94] 0.82, [0.68, 0.94] 0.90 [0.89, 0.91] 0.89 [0.88, 0.9]
Location, Texture (F19: 10a-3D-Relat-Vol-Airspaces;F21: 10c-3D-Av-Vol-AirSpaces;F22: 10d-3D-SD-Vol-AirSpaces; F201:3D-WaveP2-L2-12) 0.83 [0.70, 0.93] 0.81, [0.67, 0.92] 0.87 [0.86, 0.88] 0.86 [0.85, 0.87]
Location, Size, Texture-Runlength (F19: 10a-3D-Relat-Vol-Airspaces;F34: Volume-pxl; F37: Thickness-Pxl; F48: AvgGLN) 0.80, [0.65, 0.92] 0.80, [0.68, 0.89] 0.89 [0.89, 0.90] 0.88 [0.869, 0.893
Baseline Longest Diameter 0.76, [0.62, 0.93] 0.85, [0.35, 0.95]
Volume 0.78 [0.63, 0.91] 0.87 [0.37, 0.96]

Statistical estimates were computed using cross validation (hold out) for training and tested, randomized multiple times.