Figure 4.
A Comparison of PSs Constructed from Height-Associated versus Random SNPs Demonstrates Differences in Stratification Effects by GWAS Summary Statistics
Top row: (A and B) Height variance explained by PS (A) and east-west difference in height predicted by PS (B) as a function of p value threshold in GWAS data.
Bottom row: (C and D) Height variance explained by PS (C) and east-west difference in height predicted by PS (D) as a function of the number of independent variants in PS when all variants have a p value > 0.5 in GWAS (“random scores”). Variance explained is given as adjusted R2. In C and D, the values are based on ten random scores, and error bars in D show the range of those scores.