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Cytotoxic activity of 1–3 against several human tumor cell lines
| No. | IC50 (µM) | ||||||
|---|---|---|---|---|---|---|---|
| HL-60 | MM-231 | SMMC-7721 | A-549 | HEP3B | SW-480 | NCM460 | |
| 1 | > 40 | 12.10 ± 0.21 | 32.48 ± 0.13 | > 40 | 15.95 ± 0.15 | > 40 | > 40 |
| 2 | 28.78 ± 0.17 | 9.12 ± 0.21 | > 40 | > 40 | 8.50 ± 0.13 | 35.52 ± 0.08 | > 40 |
| 3 | > 40 | 25.45 ± 0.12 | > 40 | > 40 | 27.34 ± 0.05 | > 40 | > 40 |
| Cisplatina | 1.60 ± 0.10 | 3.82 ± 0.23 | 2.78 ± 0.15 | 2.81 ± 0.35 | 2.97 ± 0.21 | 1.45 ± 0.12 | 0.87 ± 0.10 |
aCisplatin was used as the positive control
